How to interpret an assisted reproduction clinic’s pregnancy rate
Interpreting success rates in assisted reproduction can be extremely challenging.
It is, however, a very important factor to take into consideration when deciding which clinic to choose for your fertility treatment. For this reason, at ProcreaTec, we would like to explain the different types of pregnancy rates that can be published and what they mean.
Implantation rate: Percentage of embryos that take hold in the uterus per embryo transfer.
Pregnancy rate per embryo transfer: Percentage of patients that achieve a pregnancy per embryo transfer.
Live birthrate: Percentage of patients who achieve a pregnancy after the embryo transfer and then give birth to a live child.
Cumulative pregnancy rate: Probability of pregnancy including fresh embryo transfers as well as other (subsequent) frozen embryo transfers.
When we speak about a pregnancy rate, it is also important to make a distinction between certain concepts.
* The general pregnancy rate refers to the positive results when performing a pregnancy test after an assisted reproduction treatment. It is important to note that chemical pregnancies – where the test result for pregnancy is positive, but it is impossible to visualize it via ultrasound scan – are also included in this percentage rate.
* Clinical pregnancy rate: this pregnancy can be observed via ultrasound scan, because one or more gestational sacs are visible.
At ProcreaTec, when we speak of our pregnancy rates, we always refer to clinical pregnancy rates.
Our success rates
IVF using patient’s own eggs
More than half of our patients (55%) achieve a pregnancy using their own eggs in a fresh cycle. This percentage is far superior to the one recorded as the Spanish Average by the Spanish National Fertility Society (SEF), which 36,4%. As we have mentioned on previous occasions, the age of the woman is a key factor in achieving a pregnancy. It is also true, however, that women who come to our clinic obtain very good results despite their age:
* 78% of patients under 35 get pregnant at our clinic, compared to 46,5% on average in Spain (data from the SEF).
* For patients ages 35-39, our success rate is 64% whereas the Spanish average is 37,1%.
* 33% of our patients ages 40 or over achieve pregnancy with their own eggs compared to the National Average, which is at 22,4%.
IVF- Devitrified embryo transfers and PGD cycles
Our success rate for patients who have had an IVF cycle using their own eggs and devitrified embryos is 50% for all ages. This percentage is exactly the same as that of our patients who underwent IVF with PGD (Preimplantation Genetic Diagnosis).
Our general AI success rate is 13% when using the partner’s own sperm, versus 21% when using donor sperm.
The treatment with the highest success rates is the egg donation treatment. Given that this treatment uses eggs from a younger donor, the success rate is not dependent upon the age of the recipient, but rather the quality of the donor eggs and the quality of the sperm. As such, our general success rate is 62,5% (compared to 54% which is the Spanish national average) for fresh donor egg cycles.
Spanish Fertility Society’s National Registry (SEF)
The Spanish Fertility Society’s National Registry is the official registry of assisted reproduction techniques of the Spanish Ministry of Health, Social Services and Equality. In this registry, final statistical analysis can be found, as well as the methodology used by the Spanish Fertility Society. Therefore, the institutions that accept to be audited, send all the data to this entity, which compiles it and makes it public as the national data available on all assisted reproduction treatments.
The latest data which is currently shown is from 2015. The SEF compiles data from 287 Spanish clinics who perform assisted reproduction treatments. Two main techniques are identified: IVF/ICSI (In Vitro Fertilization with IntraCytoplasmatic Sperm Injection), which is the union of an egg with a spermatozoon in the lab in order to obtain embryos which will be transferred into the uterus with the objective of achieving a gestation that is followed through to a normal newly-born baby. The second technique is the AI (Artificial Insemination), which consists of inserting sperm into the female reproductive tract in order to improve the chance of fertilization of the spermatozoon and the egg.